Effect of Pulsed Electromagnetic Field Stimulation on the Growth Plate of the Tibia Bone of Rats: An In Vivo Study

Currently, many children undergo precocious puberty, resulting in short stature due to premature closure of the growth plate. Pulsed electromagnetic field (PEMF) stimulation induces cell proliferation articular chondrocytes. We developed a method for promotion using equipment with PEMF. In this study, we aimed evaluate effects PEMF on rate plates an animal model. An experimental study was conducted 16 3-week-old rats validate care device and development by at 28 Hz 20 Gauss. The tibia bones groups without administration were dissected after 10 days, then, length plate knee levels insulin-like factor (IGF)-1 hormone serum measured. bone circulating IGF-1 significantly increased 25.6% 13.6%, respectively, group which applied compared those control group, any side effects. These results suggest that can safely stimulate non-invasive manner promote growth.